Across TCGA patient cohorts, IGFL1 mutation is significantly associated with the RNA expression of many other genes, with 640 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IGFL1-associated genes across cancer lineages are ZNF705CP, NPPA-AS1, and PRR34. Each is linked with IGFL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGFL1-to-partner and partner-to-IGFL1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGFL1→partner) and Y-score (partner→IGFL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ZNF705CP →	+0.129	+6.315	<.001	.001	3	2
UCEC	NPPA-AS1 →	+1.100	+3.502	<.001	.002	3	2
UCEC	PRR34 →	+0.216	+3.201	.002	.009	3	1
UCEC	LINC01050 →	+0.232	+2.479	.001	.003	3	1
UCEC	DOC2B →	-1.356	-3.459	<.001	.005	3	1
UCEC	SUGT1-DT →	+0.625	+3.210	.003	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 640 associations by consensus.

Exploration

IGFL1 survival (RNA) · tumor vs normal (RNA) · all IGFL1 data types