IGFBP5

Across TCGA patient cohorts, IGFBP5 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,726 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible IGFBP5-associated proteins across cancer lineages are IGFBP5_S116, TIMP2, and EFEMP2. Each is linked with IGFBP5 in more than 7 cancer types. Because this analysis shows association rather than direction, both IGFBP5-to-partner and partner-to-IGFBP5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGFBP5 versus IGFBP5_S116 in BRCA, with a Pearson correlation of 0.67.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGFBP5→partner) and Y-score (partner→IGFBP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	IGFBP5_S116 →	+1.128	+2.030	<.001	<.001	3	8
BRCA	TIMP2 →	+0.702	+1.442	<.001	<.001	3	7
GBM	EFEMP2 →	+0.713	+1.137	.002	<.001	2	8
LSCC	FNDC1 →	+0.879	+1.035	<.001	<.001	3	7
LSCC	ANGPTL2 →	+0.758	+1.206	<.001	<.001	3	7
LSCC	AEBP1 →	+0.839	+1.185	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,726 associations by consensus.

IGFBP5 vs IGFBP5_S116 — BRCA

Explore this scatter interactively →