IGFBP3

Across TCGA patient cohorts, IGFBP3 RNA expression is significantly associated with the RNA expression of many other genes, with 16,652 significant associations in total. UVM shows the largest number of these associations.

The most reproducible IGFBP3-associated genes across cancer lineages are STC1, COL5A2, and ESM1. Each is linked with IGFBP3 in more than 28 cancer types. Because this analysis shows association rather than direction, both IGFBP3-to-partner and partner-to-IGFBP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGFBP3 versus STC1 in TGCT, with a Pearson correlation of 0.79.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGFBP3→partner) and Y-score (partner→IGFBP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
TGCT	STC1 →	+2.479	+2.573	<.001	<.001	3	29
TGCT	COL5A2 →	+2.322	+2.131	<.001	<.001	3	29
TGCT	ESM1 →	+2.599	+2.514	<.001	<.001	3	28
TGCT	LOX →	+2.594	+2.541	<.001	<.001	3	28
THYM	FSTL1 →	+1.774	+1.241	<.001	<.001	3	27
ACC	COL4A1 →	+2.006	+1.581	<.001	<.001	3	27

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,652 associations by consensus.

IGFBP3 vs STC1 — TGCT

Explore this scatter interactively →