IGFBP3

Across TCGA cell cohorts, IGFBP3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,933 significant associations in total. BONE shows the largest number of these associations.

The most reproducible IGFBP3-associated GO terms across cancer lineages are Viral process, Positive regulation of miRNA metabolic process, and Wound healing. Each is linked with IGFBP3 in more than 13 cancer types. Because this analysis shows association rather than direction, both IGFBP3-to-partner and partner-to-IGFBP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Viral process grouped by IGFBP3-low versus IGFBP3-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGFBP3→partner) and Y-score (partner→IGFBP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Viral process →	+0.088	+4.077	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Positive regulation of miRNA metabolic process →	+0.105	+2.682	.001	.002	3	13
BONE	Wound healing →	+0.127	+3.379	<.001	.003	3	13
BONE	Negative regulation of smooth muscle cell migration →	+0.153	+3.423	.001	.009	3	12
BREAST	Response to water →	+0.161	+4.526	<.001	<.001	3	12
BONE	Viral life cycle →	+0.133	+4.836	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,933 associations by consensus.

Viral process by IGFBP3 expression — BREAST

Explore this box plot interactively →