IGFBP2

Across TCGA cell cohorts, IGFBP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,225 significant associations in total. BONE shows the largest number of these associations.

The most reproducible IGFBP2-associated GO terms across cancer lineages are Aerobic respiration, Regulation of DNA repair, and Positive regulation of activated T cell proliferation. Each is linked with IGFBP2 in more than 10 cancer types. Because this analysis shows association rather than direction, both IGFBP2-to-partner and partner-to-IGFBP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Aerobic respiration grouped by IGFBP2-low versus IGFBP2-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGFBP2→partner) and Y-score (partner→IGFBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Aerobic respiration →	+0.095	+4.878	<.001	<.001	3	11
OVARY	Regulation of DNA repair →	+0.040	+2.811	<.001	<.001	3	10
STOMACH	Positive regulation of activated T cell proliferation →	+0.202	+2.976	<.001	.001	3	10
STOMACH	Regulation of activated T cell proliferation →	+0.161	+3.604	<.001	<.001	3	10
BONE	Regulation of potassium ion transport →	-0.149	-5.380	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Regulation of membrane repolarization →	-0.156	-3.253	.002	.002	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,225 associations by consensus.

Aerobic respiration by IGFBP2 expression — OVARY

Explore this box plot interactively →