IGFBP1

Across TCGA patient cohorts, IGFBP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,843 significant associations in total. KIRP shows the largest number of these associations.

The most reproducible IGFBP1-associated GO terms across cancer lineages are Positive regulation of blood vessel endothelial cell migration, Negative regulation of coagulation, and Negative regulation of wound healing. Each is linked with IGFBP1 in more than 11 cancer types. Because this analysis shows association rather than direction, both IGFBP1-to-partner and partner-to-IGFBP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of blood vessel endothelial cell migration grouped by IGFBP1-low versus IGFBP1-high in TGCT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGFBP1→partner) and Y-score (partner→IGFBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
TGCT	Positive regulation of blood vessel endothelial cell migration →	+0.037	+0.408	<.001	<.001	3	12
TGCT	Negative regulation of coagulation →	+0.049	+0.446	<.001	<.001	3	12
TGCT	Negative regulation of wound healing →	+0.032	+0.294	<.001	<.001	3	12
STAD	Response to purine-containing compound →	+0.032	+0.619	<.001	.001	3	11
STAD	Regulation of coagulation →	+0.040	+0.661	<.001	.003	3	11
STAD	Regulation of glucose transmembrane transport →	+0.033	+0.623	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,843 associations by consensus.

Positive regulation of blood vessel endothelial cell migration by IGFBP1 expression — TGCT

Explore this box plot interactively →