IGF2BP3

Across TCGA patient cohorts, IGF2BP3 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,883 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IGF2BP3-associated proteins across cancer lineages are IGF2BP3_S184, TRIP13, and NOL11. Each is linked with IGF2BP3 in more than 9 cancer types. Because this analysis shows association rather than direction, both IGF2BP3-to-partner and partner-to-IGF2BP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGF2BP3 versus IGF2BP3_S184 in LUAD, with a Pearson correlation of 0.83.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGF2BP3→partner) and Y-score (partner→IGF2BP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	IGF2BP3_S184 →	+3.671	+2.080	<.001	<.001	3	10
BRCA	TRIP13 →	+0.678	+0.689	<.001	<.001	3	8
BRCA	NOL11 →	+0.353	+0.625	<.001	<.001	3	8
BRCA	PDCD11 →	+0.311	+0.755	<.001	.001	3	8
GBM	NUDT1 →	+0.546	+1.462	<.001	<.001	3	8
LSCC	DDX18 →	+0.476	+1.921	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,883 associations by consensus.

IGF2BP3 vs IGF2BP3_S184 — LUAD

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