IGF2BP2-AS1

Across TCGA pan-cancer cohorts, IGF2BP2-AS1 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated IGF2BP2-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher IGF2BP2-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated IGF2BP2-AS1 expression acts as an unfavorable survival marker, although some lineages such as UVM and SKCM show a favorable association.

KIRC, UVM, and ACC are the cancer types where IGF2BP2-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.532	0.708	<.001	154	view →
UVM	DFS	Median	III,IV	0.745	0.295	.002	90	view →
ACC	OS	Tertile	All	0.281	0.700	<.001	90	view →
BLCA	DFS	Tertile	All	0.191	0.537	<.001	44	view →
HNSC	OS	Tertile	All	0.700	0.816	<.001	40	view →
SKCM	DFS	Quartile	III,IV	0.437	0.158	.006	28	view →
LGG	DFS	Quartile	All	0.566	0.768	<.001	27	view →
KIRP	DFS	Tertile	All	0.537	0.761	.017	15	view →
SARC	OS	Median	All	0.769	0.905	.001	14	view →
KICH	OS	Quartile	III,IV	0.228	0.840	.001	13	view →
LAML	DFS	Median	All	0.286	0.461	.030	12	view →
COAD	DFS	Quartile	IV	0.316	0.622	.029	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

IGF2BP2-AS1–KIRC (DFS)

Open the KIRC breakdown →