IGF2BP1

Across TCGA patient cohorts, IGF2BP1 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,126 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IGF2BP1-associated proteins across cancer lineages are IGF2BP1_S181, ECT2_T359, and MKNK2_S437. Each is linked with IGF2BP1 in more than 8 cancer types. Because this analysis shows association rather than direction, both IGF2BP1-to-partner and partner-to-IGF2BP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGF2BP1 versus IGF2BP1_S181 in LSCC, with a Pearson correlation of 0.89.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGF2BP1→partner) and Y-score (partner→IGF2BP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	IGF2BP1_S181 →	+3.577	+2.454	<.001	<.001	3	9
LUAD	ECT2_T359 →	+0.971	+0.960	<.001	<.001	3	5
LSCC	MKNK2_S437 →	-0.452	-2.067	<.001	<.001	3	5
CCRCC	IGF2BP3 →	+1.475	+1.194	.001	<.001	3	5
LUAD	COIL_T303 →	+0.873	+0.932	<.001	<.001	3	4
HNSC	WASF2 →	-0.182	-1.431	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,126 associations by consensus.

IGF2BP1 vs IGF2BP1_S181 — LSCC

Explore this scatter interactively →