IGF2BP1

Across TCGA cell cohorts, IGF2BP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,810 significant associations in total. BONE shows the largest number of these associations.

The most reproducible IGF2BP1-associated GO terms across cancer lineages are DNA-templated transcription initiation, Transcription initiation at RNA polymerase II promoter, and Nucleic acid transport. Each is linked with IGF2BP1 in more than 13 cancer types. Because this analysis shows association rather than direction, both IGF2BP1-to-partner and partner-to-IGF2BP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated transcription initiation grouped by IGF2BP1-low versus IGF2BP1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGF2BP1→partner) and Y-score (partner→IGF2BP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	DNA-templated transcription initiation →	+0.096	+3.607	<.001	<.001	3	14
BONE	Transcription initiation at RNA polymerase II promoter →	+0.075	+3.478	<.001	<.001	3	14
OESOPHAGUS	Nucleic acid transport →	+0.103	+1.882	<.001	<.001	3	13
OESOPHAGUS	RNA transport →	+0.103	+1.882	<.001	<.001	3	13
STOMACH	Establishment of RNA localization →	+0.096	+2.826	<.001	<.001	3	13
OESOPHAGUS	Protein-RNA complex assembly →	+0.122	+2.941	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,810 associations by consensus.

DNA-templated transcription initiation by IGF2BP1 expression — BONE

Explore this box plot interactively →