IGF2

Across TCGA patient cohorts, IGF2 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,977 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible IGF2-associated proteins across cancer lineages are COL3A1, APBB2, and SSC5D. Each is linked with IGF2 in more than 4 cancer types. Because this analysis shows association rather than direction, both IGF2-to-partner and partner-to-IGF2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGF2 versus COL3A1 in BRCA, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGF2→partner) and Y-score (partner→IGF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	COL3A1 →	+0.683	+0.371	<.001	.005	3	5
BRCA	APBB2 →	+0.528	+0.578	<.001	.002	3	5
BRCA	SSC5D →	+1.407	+0.734	<.001	<.001	3	4
UCEC	CPXM1 →	+0.594	+1.732	<.001	.003	3	4
BRCA	PHLDB1 →	+0.460	+0.380	<.001	.004	3	4
BRCA	OLFML3 →	+1.101	+0.532	<.001	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,977 associations by consensus.

IGF2 vs COL3A1 — BRCA

Explore this scatter interactively →