IGF1R

Across TCGA patient cohorts, IGF1R RNA expression is significantly associated with the RNA expression of many other genes, with 20,762 significant associations in total. UVM shows the largest number of these associations.

The most reproducible IGF1R-associated genes across cancer lineages are SNRNP200, ZNF507, and RBM12B. Each is linked with IGF1R in more than 33 cancer types. Because this analysis shows association rather than direction, both IGF1R-to-partner and partner-to-IGF1R results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGF1R versus SNRNP200 in ACC, with a Pearson correlation of 0.57.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGF1R→partner) and Y-score (partner→IGF1R) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ACC	SNRNP200 →	+1.288	+1.742	<.001	<.001	3	34
SCLC	ZNF507 →	+1.020	+1.809	<.001	<.001	3	34
DLBC	RBM12B →	+1.074	+0.771	<.001	<.001	3	34
ACC	FAM168B →	+1.279	+1.064	<.001	<.001	3	34
DLBC	KAT6B →	+1.227	+0.769	<.001	.001	3	34
ACC	FUBP1 →	+1.086	+0.994	<.001	<.001	3	34

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,762 associations by consensus.

IGF1R vs SNRNP200 — ACC

Explore this scatter interactively →