Across TCGA pan-cancer cohorts, IGBP1P3 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of IGBP1P3’s most consistent transcriptional readouts.
The strongest signal is observed in thyroid carcinoma (THCA), where IGBP1P3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types IGBP1P3 is over-expressed in tumor.
THCA are the cancer types where IGBP1P3 tumor–normal differential expression is most reproducible.