IFT80

Across TCGA cell cohorts, IFT80 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,390 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible IFT80-associated GO terms across cancer lineages are Regulation of organelle assembly, Protein desumoylation, and Intraciliary anterograde transport. Each is linked with IFT80 in more than 16 cancer types. Because this analysis shows association rather than direction, both IFT80-to-partner and partner-to-IFT80 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of organelle assembly grouped by IFT80-low versus IFT80-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IFT80→partner) and Y-score (partner→IFT80) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Regulation of organelle assembly →	+0.051	+0.983	<.001	<.001	3	17
LUNG_SCLC	Protein desumoylation →	+0.126	+0.650	<.001	<.001	3	16
URINARY_TRACT	Intraciliary anterograde transport →	+0.113	+1.227	<.001	<.001	3	16
OESOPHAGUS	Establishment of protein localization to vacuole →	+0.092	+1.046	<.001	<.001	3	15
STOMACH	Regulation of cellular response to heat →	+0.126	+0.790	<.001	<.001	3	15
STOMACH	Positive regulation of organelle assembly →	+0.067	+0.737	.001	.002	2	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,390 associations by consensus.

Regulation of organelle assembly by IFT80 expression — URINARY_TRACT

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