IFT57

Across TCGA patient cohorts, IFT57 protein abundance is significantly associated with the RNA expression of many other genes, with 13,122 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible IFT57-associated genes across cancer lineages are CCDC40, LRRC43, and CFAP99. Each is linked with IFT57 in more than 5 cancer types. Because this analysis shows association rather than direction, both IFT57-to-partner and partner-to-IFT57 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IFT57 versus CCDC40 in BRCA, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFT57→partner) and Y-score (partner→IFT57) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CCDC40 →	+0.766	+0.335	<.001	<.001	3	6
UCEC	LRRC43 →	+1.072	+0.416	<.001	<.001	3	6
UCEC	CFAP99 →	+0.978	+0.311	<.001	<.001	3	6
UCEC	CCDC114 →	+1.385	+0.381	<.001	<.001	3	5
BRCA	CEP126 →	+0.842	+0.309	<.001	<.001	3	5
UCEC	TTLL9 →	+1.172	+0.456	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,122 associations by consensus.

IFT57 vs CCDC40 — BRCA

Explore this scatter interactively →