IFT57

Across TCGA cell cohorts, IFT57 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,743 significant associations in total. BONE shows the largest number of these associations.

The most reproducible IFT57-associated GO terms across cancer lineages are Protein localization to cilium, Protein localization to ciliary transition zone, and Protein localization to ciliary membrane. Each is linked with IFT57 in more than 11 cancer types. Because this analysis shows association rather than direction, both IFT57-to-partner and partner-to-IFT57 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to cilium grouped by IFT57-low versus IFT57-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IFT57→partner) and Y-score (partner→IFT57) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Protein localization to cilium →	+0.061	+1.675	<.001	<.001	3	12
BREAST	Protein localization to ciliary transition zone →	+0.097	+1.633	<.001	<.001	3	10
CNS	Protein localization to ciliary membrane →	+0.086	+0.969	<.001	<.001	3	9
LUNG_SCLC	Microtubule-based transport →	+0.039	+0.998	.004	<.001	3	9
URINARY_TRACT	Somatic hypermutation of immunoglobulin genes →	+0.103	+1.011	.002	<.001	3	9
URINARY_TRACT	Somatic diversification of immune receptors via somatic mutation →	+0.103	+1.011	.002	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,743 associations by consensus.

Protein localization to cilium by IFT57 expression — BREAST

Explore this box plot interactively →