IFT22

Across TCGA patient cohorts, IFT22 protein abundance is significantly associated with the RNA expression of many other genes, with 14,433 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible IFT22-associated genes across cancer lineages are CEP126, SAMD15, and CFAP69. Each is linked with IFT22 in more than 6 cancer types. Because this analysis shows association rather than direction, both IFT22-to-partner and partner-to-IFT22 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IFT22 versus CEP126 in BRCA, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFT22→partner) and Y-score (partner→IFT22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CEP126 →	+1.135	+0.305	<.001	<.001	3	7
BRCA	SAMD15 →	+1.259	+0.366	<.001	<.001	3	6
BRCA	CFAP69 →	+1.119	+0.377	<.001	<.001	3	6
UCEC	TTC26 →	+0.602	+0.333	<.001	<.001	3	6
BRCA	NEK11 →	+0.997	+0.336	<.001	<.001	3	6
UCEC	DNAH6 →	+1.583	+0.529	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,433 associations by consensus.

IFT22 vs CEP126 — BRCA

Explore this scatter interactively →