Across TCGA patient cohorts, IFT140 protein abundance is significantly associated with the RNA expression of many other genes, with 16,310 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible IFT140-associated genes across cancer lineages are CFAP69, MDH1B, and CFAP91. Each is linked with IFT140 in more than 7 cancer types. Because this analysis shows association rather than direction, both IFT140-to-partner and partner-to-IFT140 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFT140→partner) and Y-score (partner→IFT140) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CFAP69 →	+1.269	+0.600	<.001	<.001	3	8
UCEC	MDH1B →	+1.239	+0.395	<.001	<.001	3	8
BRCA	CFAP91 →	+1.238	+0.574	<.001	<.001	3	8
BRCA	CCDC30 →	+0.758	+0.613	<.001	<.001	3	8
UCEC	CFAP43 →	+2.041	+0.472	<.001	<.001	3	8
UCEC	TTC25 →	+1.353	+0.438	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,310 associations by consensus.

Exploration

IFT140 survival (RNA) · tumor vs normal (RNA) · all IFT140 data types