IFT122

Across TCGA patient cohorts, IFT122 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,925 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible IFT122-associated proteins across cancer lineages are DBR1, TTC21B, and WDR35. Each is linked with IFT122 in more than 6 cancer types. Because this analysis shows association rather than direction, both IFT122-to-partner and partner-to-IFT122 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IFT122 versus DBR1 in LSCC, with a Pearson correlation of 0.54.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IFT122→partner) and Y-score (partner→IFT122) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DBR1 →	+0.285	+0.485	<.001	<.001	3	7
UCEC	TTC21B →	+0.257	+0.622	<.001	<.001	3	5
UCEC	WDR35 →	+0.338	+0.613	<.001	<.001	3	5
LSCC	DPCD →	+0.721	+0.732	<.001	<.001	3	5
UCEC	IFT22 →	+0.399	+0.583	<.001	<.001	3	5
BRCA	RCOR3 →	+0.418	+0.729	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,925 associations by consensus.

IFT122 vs DBR1 — LSCC

Explore this scatter interactively →