IFT122

Across TCGA cell cohorts, IFT122 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,517 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible IFT122-associated GO terms across cancer lineages are Regulation of sister chromatid cohesion, Microtubule cytoskeleton organization involved in mitosis, and Regulation of chromosome organization. Each is linked with IFT122 in more than 17 cancer types. Because this analysis shows association rather than direction, both IFT122-to-partner and partner-to-IFT122 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of sister chromatid cohesion grouped by IFT122-low versus IFT122-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IFT122→partner) and Y-score (partner→IFT122) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Regulation of sister chromatid cohesion →	+0.131	+0.950	<.001	<.001	3	18
BLOOD_Myeloma	Microtubule cytoskeleton organization involved in mitosis →	+0.099	+0.915	<.001	.001	3	17
BONE	Regulation of chromosome organization →	+0.104	+0.950	.006	.001	3	17
SOFT_TISSUE	Nuclear export →	+0.085	+0.859	<.001	<.001	3	17
BONE	RNA localization →	+0.111	+0.730	<.001	.005	3	17
UPPER_AERODIGESTIVE_TRACT	DNA damage checkpoint signaling →	+0.089	+1.016	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,517 associations by consensus.

Regulation of sister chromatid cohesion by IFT122 expression — BLOOD_Myeloma

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