Across TCGA patient cohorts, IFRD2 protein abundance is significantly associated with the RNA expression of many other genes, with 5,570 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible IFRD2-associated genes across cancer lineages are IMPDH2, PRKD1, and SELENOM. Each is linked with IFRD2 in more than 3 cancer types. Because this analysis shows association rather than direction, both IFRD2-to-partner and partner-to-IFRD2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFRD2→partner) and Y-score (partner→IFRD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	IMPDH2 →	+0.530	+0.458	<.001	<.001	3	3
HNSC	PRKD1 →	-0.731	-0.362	.002	.001	3	3
LSCC	SELENOM →	-0.592	-0.260	<.001	<.001	3	3
LSCC	FAM229B →	-0.716	-0.444	<.001	<.001	3	3
UCEC	HOMER3 →	-0.601	-0.363	.007	.001	3	3
LSCC	NUAK1 →	-0.699	-0.289	.001	.003	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,570 associations by consensus.

Exploration

IFRD2 survival (RNA) · tumor vs normal (RNA) · all IFRD2 data types