Across TCGA patient cohorts, IFRD2 mutation is significantly associated with the RNA expression of many other genes, with 1,031 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IFRD2-associated genes across cancer lineages are PINK1-AS, ABCC6P2, and CDH12P3. Each is linked with IFRD2 in more than 2 cancer types. Because this analysis shows association rather than direction, both IFRD2-to-partner and partner-to-IFRD2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFRD2→partner) and Y-score (partner→IFRD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	PINK1-AS →	+0.469	+2.623	.002	.005	3	3
UCEC	ABCC6P2 →	-0.425	-3.652	.007	.001	3	3
CESC	CDH12P3 →	+0.257	+5.969	<.001	.002	3	2
UCEC	ZDHHC7 →	+0.409	+3.223	.006	.009	3	2
UCEC	TRIM17 →	-1.388	-3.700	<.001	.001	3	2
UCEC	MOCS2 →	+0.439	+2.928	.005	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,031 associations by consensus.

Exploration

IFRD2 survival (RNA) · tumor vs normal (RNA) · all IFRD2 data types