IFRD1

Across TCGA patient cohorts, IFRD1 protein abundance is significantly associated with the RNA expression of many other genes, with 9,164 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IFRD1-associated genes across cancer lineages are SBDSP1, DNAJC2, and UBA2. Each is linked with IFRD1 in more than 3 cancer types. Because this analysis shows association rather than direction, both IFRD1-to-partner and partner-to-IFRD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IFRD1 versus SBDSP1 in COAD, with a Pearson correlation of 0.74.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFRD1→partner) and Y-score (partner→IFRD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SBDSP1 →	+1.120	+1.423	<.001	.001	3	4
COAD	DNAJC2 →	+0.816	+1.204	.001	.001	3	3
COAD	UBA2 →	+0.918	+1.408	.004	.009	3	3
LSCC	CEBPG →	+0.648	+0.457	<.001	<.001	3	3
COAD	LRWD1 →	+0.753	+1.371	.001	.001	3	3
COAD	DDIT3 →	+1.216	+1.278	.006	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,164 associations by consensus.

IFRD1 vs SBDSP1 — COAD

Explore this scatter interactively →