IFNWP19

Across TCGA pan-cancer cohorts, IFNWP19 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of IFNWP19’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where IFNWP19 RNA is repressed in tumor relative to normal tissue. In most cancer types IFNWP19 is over-expressed in tumor, although a few such as KIRC and KICH show the opposite, repressed pattern.

KIRC, THCA, and HNSC are the cancer types where IFNWP19 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in IFNWP19 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	II,III,IV	−0.983	<.001	12	view →
THCA	Male	III,IV	+2.387	<.001	11	view →
HNSC	All	All	+1.223	<.001	9	view →
KICH	All	II,III,IV	−1.350	<.001	8	view →
LUAD	All	II,III,IV	+1.282	<.001	8	view →
LUSC	Male	II,III,IV	+1.308	<.001	6	view →
BRCA	Female	All	−0.695	<.001	6	view →
COAD	All	II,III,IV	+0.588	<.001	5	view →
KIRP	Male	All	+0.839	.010	3	view →
PRAD	All	All	−0.619	<.001	2	view →
LUSC	Female	III,IV	−0.169	.003	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 10 lineages.

IFNWP19–KIRC

Open the KIRC breakdown →