IFNGR1

Across TCGA pan-cancer cohorts, IFNGR1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated IFNGR1 data layer compared with 25 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher IFNGR1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated IFNGR1 expression acts as an unfavorable survival marker.

LUAD, UCEC, and PDAC are the cancer types where IFNGR1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Tertile	II,III,IV	0.573	0.932	.024	12	view →
UCEC	DFS	Median	All	0.875	1.000	.040	8	view →
PDAC	DFS	Median	III,IV	0.537	0.919	.024	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

IFNGR1–LUAD (DFS)

Open the LUAD breakdown →