IFNGR1

Across TCGA patient cohorts, IFNGR1 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,208 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IFNGR1-associated proteins across cancer lineages are LUC7L3, MYO1G, and NHP2. Each is linked with IFNGR1 in more than 5 cancer types. Because this analysis shows association rather than direction, both IFNGR1-to-partner and partner-to-IFNGR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IFNGR1 versus LUC7L3 in LSCC, with a Pearson correlation of -0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IFNGR1→partner) and Y-score (partner→IFNGR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	LUC7L3 →	-0.296	-0.611	<.001	<.001	3	6
GBM	MYO1G →	+0.485	+0.438	<.001	<.001	3	6
COAD	NHP2 →	-0.403	-0.698	<.001	<.001	3	6
OV	HNRNPU →	-0.514	-0.535	<.001	<.001	3	6
OV	ARHGEF6 →	+0.480	+0.594	<.001	.005	3	5
HNSC	INPP1 →	+0.609	+0.458	<.001	.001	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,208 associations by consensus.

IFNGR1 vs LUC7L3 — LSCC

Explore this scatter interactively →