IFNGR1

Across TCGA patient cohorts, IFNGR1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,258 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IFNGR1-associated genes across cancer lineages are TUBG1P, THSD7B, and RNF103-CHMP3. Each is linked with IFNGR1 in more than 3 cancer types. Because this analysis shows association rather than direction, both IFNGR1-to-partner and partner-to-IFNGR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IFNGR1 versus TUBG1P in HNSC, with a Pearson correlation of -0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFNGR1→partner) and Y-score (partner→IFNGR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TUBG1P →	-0.530	-0.390	<.001	<.001	3	4
LSCC	THSD7B →	-0.794	-0.171	<.001	.004	3	3
LSCC	RNF103-CHMP3 →	-0.231	-0.236	.002	.002	3	3
GBM	ADORA3 →	+0.975	+0.334	<.001	<.001	3	3
UCEC	DENND3 →	+0.820	+0.580	.001	.002	3	3
GBM	CCDC34 →	-0.707	-0.539	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,258 associations by consensus.

IFNGR1 vs TUBG1P — HNSC

Explore this scatter interactively →