IFNGR1

Across TCGA cell cohorts, IFNGR1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,613 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible IFNGR1-associated GO terms across cancer lineages are Astrocyte activation, Type II interferon-mediated signaling pathway, and Astrocyte development. Each is linked with IFNGR1 in more than 15 cancer types. Because this analysis shows association rather than direction, both IFNGR1-to-partner and partner-to-IFNGR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Astrocyte activation grouped by IFNGR1-low versus IFNGR1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IFNGR1→partner) and Y-score (partner→IFNGR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Astrocyte activation →	+0.235	+1.084	<.001	<.001	3	16
BREAST	Type II interferon-mediated signaling pathway →	+0.244	+1.343	<.001	<.001	3	15
STOMACH	Astrocyte development →	+0.188	+1.156	<.001	<.001	3	14
URINARY_TRACT	Negative regulation of amyloid-beta clearance →	+0.135	+1.156	.002	<.001	3	14
URINARY_TRACT	Glial cell activation →	+0.194	+0.993	<.001	<.001	3	14
BLOOD_Leukemia	Post-translational protein targeting to membrane, translocation →	+0.093	+0.975	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,613 associations by consensus.

Astrocyte activation by IFNGR1 expression — OVARY

Explore this box plot interactively →