Across TCGA patient cohorts, IFNE RNA expression is significantly associated with the protein abundance of many other proteins, with 7,590 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IFNE-associated proteins across cancer lineages are MTAP, LPCAT2, and MYO1E. Each is linked with IFNE in more than 3 cancer types. Because this analysis shows association rather than direction, both IFNE-to-partner and partner-to-IFNE results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IFNE→partner) and Y-score (partner→IFNE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MTAP →	+0.574	+1.315	<.001	<.001	3	4
LSCC	LPCAT2 →	+0.374	+1.096	<.001	<.001	3	4
HNSC	MYO1E →	+0.258	+0.989	.003	.009	3	3
UCEC	PCDH7_S1011 →	+0.745	+1.230	.002	.001	3	3
LSCC	PCF11_S777 →	-0.406	-0.974	<.001	.001	3	3
LSCC	S100A2 →	+1.238	+0.719	.002	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,590 associations by consensus.

Exploration

IFNE survival (RNA) · tumor vs normal (RNA) · all IFNE data types