Across TCGA patient cohorts, IFNE mutation is significantly associated with the RNA expression of many other genes, with 499 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IFNE-associated genes across cancer lineages are RN7SL91P, RNA5SP245, and MTND4LP19. Each is linked with IFNE in more than 1 cancer types. Because this analysis shows association rather than direction, both IFNE-to-partner and partner-to-IFNE results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFNE→partner) and Y-score (partner→IFNE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SL91P →	+0.124	+4.771	<.001	.006	3	2
LUAD	RNA5SP245 →	+0.620	+3.659	.002	.005	3	2
LUAD	MTND4LP19 →	+0.137	+4.523	<.001	.004	3	2
LUAD	RN7SL98P →	+0.114	+3.491	<.001	.002	3	2
LUAD	RNU6-1137P →	+0.271	+3.480	<.001	.005	3	2
UCEC	AARSD1 →	+0.418	+2.700	.003	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 499 associations by consensus.

Exploration

IFNE survival (RNA) · tumor vs normal (RNA) · all IFNE data types