Across TCGA cell cohorts, IFNE RNA expression is significantly associated with the go_rna of many other GO terms, with 3,646 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible IFNE-associated GO terms across cancer lineages are Natural killer cell activation involved in immune response, Positive regulation of canonical NF-kappaB signal transduction, and Small GTPase-mediated signal transduction. Each is linked with IFNE in more than 9 cancer types. Because this analysis shows association rather than direction, both IFNE-to-partner and partner-to-IFNE results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IFNE→partner) and Y-score (partner→IFNE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Natural killer cell activation involved in immune response →	-0.359	-1.038	<.001	.001	3	10
BONE	Positive regulation of canonical NF-kappaB signal transduction →	+0.074	+0.428	<.001	.009	3	10
OVARY	Small GTPase-mediated signal transduction →	+0.053	+0.784	<.001	<.001	3	9
LUNG_NSCLC_LUSC	Regulation of corticosterone secretion →	+0.194	+0.987	.005	.002	3	9
SKIN	Positive regulation of cell maturation →	-0.185	-0.578	<.001	<.001	3	8
BREAST	Regulation of cell-matrix adhesion →	+0.086	+0.623	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,646 associations by consensus.

Exploration

IFNE survival (RNA) · tumor vs normal (RNA) · all IFNE data types