IFNA21

Across TCGA patient cohorts, IFNA21 protein abundance is significantly associated with the RNA expression of many other genes, with 251 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible IFNA21-associated genes across cancer lineages are CTSG, R3HDML, and UBL4A. Each is linked with IFNA21 in more than 1 cancer types. Because this analysis shows association rather than direction, both IFNA21-to-partner and partner-to-IFNA21 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IFNA21 versus CTSG in BRCA, with a Pearson correlation of -0.92.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFNA21→partner) and Y-score (partner→IFNA21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CTSG →	-3.303	-0.853	.004	.008	3	1
BRCA	R3HDML →	-0.173	-0.764	.003	.005	3	1
BRCA	UBL4A →	+0.836	+0.926	<.001	.001	3	1
BRCA	SLC30A4 →	-1.240	-0.776	<.001	.008	3	1
BRCA	STX10 →	+0.492	+0.669	.004	.007	3	1
BRCA	CLIP3 →	-1.537	-0.757	.003	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 251 associations by consensus.

IFNA21 vs CTSG — BRCA

Explore this scatter interactively →