IFNA17

Across TCGA patient cohorts, IFNA17 mutation is significantly associated with the RNA expression of many other genes, with 853 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IFNA17-associated genes across cancer lineages are LINC01737, RNA5SP419, and RNA5SP408. Each is linked with IFNA17 in more than 2 cancer types. Because this analysis shows association rather than direction, both IFNA17-to-partner and partner-to-IFNA17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01737 grouped by IFNA17-low versus IFNA17-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFNA17→partner) and Y-score (partner→IFNA17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	LINC01737 →	+0.128	+5.912	<.001	.002	3	3
UCEC	RNA5SP419 →	+0.672	+2.661	<.001	.001	3	2
UCEC	RNA5SP408 →	+0.326	+2.865	.001	.004	3	2
LUSC	RNA5SP417 →	+1.136	+5.882	<.001	.002	3	2
LUSC	RNA5SP413 →	+1.733	+6.081	<.001	.002	3	2
LUSC	RNU6-1212P →	+0.846	+5.211	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 853 associations by consensus.

LINC01737 by IFNA17 expression — HNSC

Explore this box plot interactively →