IFNA17

Across TCGA pan-cancer cohorts, IFNA17 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated IFNA17 data layer compared with 3 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher IFNA17 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated IFNA17 expression acts as an unfavorable survival marker, although some lineages such as OV show a favorable association.

UCEC, STAD, and LIHC are the cancer types where IFNA17 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Tertile	II,III,IV	0.201	0.771	<.001	90	view →
STAD	DFS	Tertile	All	0.426	0.678	<.001	72	view →
LIHC	OS	Tertile	III,IV	0.092	0.649	<.001	63	view →
BLCA	OS	Tertile	All	0.119	0.693	<.001	54	view →
KIRC	DFS	Tertile	III,IV	0.394	0.759	.012	42	view →
THCA	OS	Tertile	III,IV	0.240	0.795	.006	21	view →
UCS	DFS	Tertile	All	0.136	0.523	.034	18	view →
OV	OS	Tertile	All	0.966	0.683	.038	18	view →
SARC	DFS	Tertile	All	0.337	0.614	.021	18	view →
LUSC	DFS	Tertile	II,III,IV	0.286	0.711	.011	18	view →
LGG	DFS	Tertile	All	0.137	0.421	.016	9	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

IFNA17–UCEC (OS)

Open the UCEC breakdown →