Across TCGA patient cohorts, IFNA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,774 significant associations in total. STAD shows the largest number of these associations.

The most reproducible IFNA1-associated GO terms across cancer lineages are Regulation of protein deubiquitination, Keratinocyte differentiation, and Rap protein signal transduction. Each is linked with IFNA1 in more than 12 cancer types. Because this analysis shows association rather than direction, both IFNA1-to-partner and partner-to-IFNA1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IFNA1→partner) and Y-score (partner→IFNA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of protein deubiquitination →	+0.089	+0.116	<.001	<.001	3	13
ESCA	Keratinocyte differentiation →	+0.077	+0.174	<.001	<.001	3	13
STAD	Rap protein signal transduction →	+0.058	+0.121	<.001	<.001	3	13
STAD	Exocrine system development →	+0.044	+0.088	<.001	<.001	3	13
STAD	Trachea development →	+0.062	+0.101	<.001	<.001	3	12
STAD	Positive regulation of NF-kappaB transcription factor activity →	+0.053	+0.131	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,774 associations by consensus.

Exploration

IFNA1 survival (RNA) · tumor vs normal (RNA) · all IFNA1 data types