Across TCGA patient cohorts, IFNA1 mutation is significantly associated with the total protein of many other genes, with 9 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IFNA1-associated genes across cancer lineages are INPP4B, Ku80, and p70-S6K. Each is linked with IFNA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both IFNA1-to-partner and partner-to-IFNA1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFNA1→partner) and Y-score (partner→IFNA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	INPP4B →	-0.403	-3.169	.023	.019	3	1
UCEC	Ku80 →	+0.324	+3.183	.012	.010	3	1
UCEC	p70-S6K →	+0.212	+3.196	.045	.010	3	1
UCEC	Tuberin →	+0.365	+2.817	.013	.036	3	1
UCEC	Caspase-8 →	-0.349	-3.169	.011	.020	2	1
UCEC	4E-BP1 →	+0.385	+2.837	.009	.035	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Exploration

IFNA1 survival (RNA) · tumor vs normal (RNA) · all IFNA1 data types