Across TCGA patient cohorts, IFITM5 mutation is significantly associated with the RNA expression of many other genes, with 41 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IFITM5-associated genes across cancer lineages are MIR7702, MIR6780A, and MIR6809. Each is linked with IFITM5 in more than 1 cancer types. Because this analysis shows association rather than direction, both IFITM5-to-partner and partner-to-IFITM5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFITM5→partner) and Y-score (partner→IFITM5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR7702 →	+0.537	+5.738	<.001	<.001	3	1
UCEC	MIR6780A →	+0.702	+3.386	<.001	.008	3	1
SKCM	MIR6809 →	+0.357	+5.771	<.001	.003	3	1
COAD	SRY →	+0.398	+5.357	<.001	.006	3	1
COAD	OR52X1P →	+0.068	+5.145	.003	.007	3	1
COAD	MIR4698 →	+0.546	+5.212	.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

Exploration

IFITM5 survival (RNA) · tumor vs normal (RNA) · all IFITM5 data types