Across TCGA patient cohorts, IFITM2 mutation is significantly associated with the RNA expression of many other genes, with 132 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IFITM2-associated genes across cancer lineages are RNU6-281P, GOLGA6C, and OR4M1. Each is linked with IFITM2 in more than 1 cancer types. Because this analysis shows association rather than direction, both IFITM2-to-partner and partner-to-IFITM2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFITM2→partner) and Y-score (partner→IFITM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU6-281P →	+0.373	+7.816	<.001	.008	3	2
UCEC	GOLGA6C →	+0.061	+3.302	<.001	.009	3	1
UCEC	OR4M1 →	+0.058	+3.827	.003	.003	3	1
UCEC	C2orf83 →	+0.235	+3.962	<.001	.003	3	1
SKCM	OFD1P11Y →	+0.039	+7.816	<.001	.008	3	1
UCEC	AQP7P3 →	+0.066	+4.260	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 132 associations by consensus.

Exploration

IFITM2 survival (RNA) · tumor vs normal (RNA) · all IFITM2 data types