IFITM10

Across TCGA patient cohorts, IFITM10 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,162 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible IFITM10-associated GO terms across cancer lineages are Negative regulation of phospholipid metabolic process, Positive regulation of macrophage migration, and Antigen processing and presentation of peptide or polysaccharide antigen via MHC class II. Each is linked with IFITM10 in more than 19 cancer types. Because this analysis shows association rather than direction, both IFITM10-to-partner and partner-to-IFITM10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of phospholipid metabolic process grouped by IFITM10-low versus IFITM10-high in PCPG.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IFITM10→partner) and Y-score (partner→IFITM10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PCPG	Negative regulation of phospholipid metabolic process →	+0.059	+1.206	<.001	<.001	3	19
DLBC	Positive regulation of macrophage migration →	+0.074	+1.234	<.001	<.001	3	19
SCLC	Antigen processing and presentation of peptide or polysaccharide antigen via MHC class II →	+0.283	+0.917	.002	.001	3	19
DLBC	Macrophage migration →	+0.056	+0.965	<.001	<.001	2	19
LAML	Negative regulation of antigen processing and presentation →	+0.070	+0.665	<.001	<.001	3	18
SCLC	Positive regulation of regulatory T cell differentiation →	+0.100	+0.650	.006	.009	1	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,162 associations by consensus.

Negative regulation of phospholipid metabolic process by IFITM10 expression — PCPG

Explore this box plot interactively →