IFITM10

Across TCGA pan-cancer cohorts, IFITM10 RNA is linked to patient survival in 29 of 34 cancer types, making it the most broadly survival-associated IFITM10 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher IFITM10 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated IFITM10 expression acts as an unfavorable survival marker, although some lineages such as LGG and STAD show a favorable association.

MESO, KIRP, and LGG are the cancer types where IFITM10 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Quartile	III,IV	0.385	0.697	.002	60	view →
KIRP	DFS	Tertile	II,III,IV	0.227	0.940	.003	59	view →
LGG	OS	Median	All	0.909	0.705	<.001	54	view →
KIRC	DFS	Quartile	All	0.532	0.742	<.001	50	view →
LIHC	OS	Median	III,IV	0.428	0.774	<.001	48	view →
COAD	OS	Quartile	II,III,IV	0.398	0.721	.001	43	view →
THCA	DFS	Median	III,IV	0.515	0.927	.001	31	view →
CHOL	OS	Median	All	0.172	1.000	<.001	26	view →
STAD	DFS	Quartile	All	0.648	0.416	.006	25	view →
GBM	OS	Tertile	All	0.252	0.541	<.001	21	view →
LUAD	DFS	Tertile	III,IV	0.585	0.813	.013	18	view →
ACC	OS	Quartile	II,III,IV	0.669	0.898	.014	17	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 29 lineages.

IFITM10–MESO (OS)

Open the MESO breakdown →