IFIT5

Across TCGA patient cohorts, IFIT5 protein abundance is significantly associated with the RNA expression of many other genes, with 9,372 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IFIT5-associated genes across cancer lineages are IFIT3, CMPK2, and IFI44L. Each is linked with IFIT5 in more than 9 cancer types. Because this analysis shows association rather than direction, both IFIT5-to-partner and partner-to-IFIT5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IFIT5 versus IFIT3 in LSCC, with a Pearson correlation of 0.81.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFIT5→partner) and Y-score (partner→IFIT5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	IFIT3 →	+1.731	+0.430	<.001	<.001	3	10
LSCC	CMPK2 →	+1.429	+0.420	<.001	<.001	3	10
LSCC	IFI44L →	+1.990	+0.467	<.001	<.001	3	10
HNSC	IFI44 →	+2.162	+0.774	<.001	<.001	3	10
HNSC	PARP9 →	+1.464	+0.765	<.001	<.001	3	10
BRCA	HERC6 →	+1.346	+0.414	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,372 associations by consensus.

IFIT5 vs IFIT3 — LSCC

Explore this scatter interactively →