IFIT3

Across TCGA patient cohorts, IFIT3 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,230 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IFIT3-associated proteins across cancer lineages are OAS2, PARP14, and STAT1. Each is linked with IFIT3 in more than 9 cancer types. Because this analysis shows association rather than direction, both IFIT3-to-partner and partner-to-IFIT3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IFIT3 versus OAS2 in LSCC, with a Pearson correlation of 0.85.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IFIT3→partner) and Y-score (partner→IFIT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	OAS2 →	+1.132	+1.792	<.001	<.001	3	10
BRCA	PARP14 →	+0.488	+1.730	<.001	<.001	3	10
BRCA	STAT1 →	+0.753	+1.676	<.001	<.001	3	10
LSCC	TAPBP →	+0.690	+1.316	<.001	<.001	3	10
HNSC	TRIM21 →	+0.530	+1.492	<.001	<.001	3	10
HNSC	UBE2L6 →	+0.769	+1.975	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,230 associations by consensus.

IFIT3 vs OAS2 — LSCC

Explore this scatter interactively →