IFIT3

Across TCGA patient cohorts, IFIT3 protein abundance is significantly associated with the RNA expression of many other genes, with 10,196 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible IFIT3-associated genes across cancer lineages are ETV7, DDX58, and OAS3. Each is linked with IFIT3 in more than 9 cancer types. Because this analysis shows association rather than direction, both IFIT3-to-partner and partner-to-IFIT3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IFIT3 versus ETV7 in BRCA, with a Pearson correlation of 0.59.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFIT3→partner) and Y-score (partner→IFIT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ETV7 →	+1.349	+0.775	<.001	<.001	3	10
HNSC	DDX58 →	+1.402	+1.292	<.001	<.001	3	10
OV	OAS3 →	+1.479	+0.778	<.001	<.001	3	10
OV	OAS2 →	+1.665	+0.844	<.001	<.001	3	10
HNSC	IFIH1 →	+1.407	+1.341	<.001	<.001	3	10
HNSC	STAT1 →	+1.171	+1.208	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,196 associations by consensus.

IFIT3 vs ETV7 — BRCA

Explore this scatter interactively →