Across TCGA pan-cancer cohorts, IFIT1B Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated IFIT1B data layer compared with 17 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher IFIT1B Mutation is associated with better disease-free survival. In most high-consensus cancer types, elevated IFIT1B expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

UCEC and SKCM are the cancer types where IFIT1B Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	1.000	0.830	.027	22	view →
SKCM	DFS	Median	II,III,IV	0.063	0.708	<.001	6	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: IFIT1B tumor-vs-normal RNA expression · all IFIT1B data types