IFI44L

Across TCGA patient cohorts, IFI44L protein abundance is significantly associated with the RNA expression of many other genes, with 7,284 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible IFI44L-associated genes across cancer lineages are HERC6, MX1, and OAS3. Each is linked with IFI44L in more than 7 cancer types. Because this analysis shows association rather than direction, both IFI44L-to-partner and partner-to-IFI44L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IFI44L versus HERC6 in HNSC, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFI44L→partner) and Y-score (partner→IFI44L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	HERC6 →	+1.112	+0.804	<.001	<.001	3	8
COAD	MX1 →	+1.965	+1.001	<.001	.004	2	8
UCEC	OAS3 →	+1.149	+1.375	.001	<.001	3	7
UCEC	OAS2 →	+1.546	+1.092	.001	.001	3	7
HNSC	IFIT3 →	+1.575	+0.909	<.001	<.001	3	7
HNSC	IFIT2 →	+1.390	+0.985	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,284 associations by consensus.

IFI44L vs HERC6 — HNSC

Explore this scatter interactively →