IFI27L1

Across TCGA patient cohorts, IFI27L1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,416 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IFI27L1-associated proteins across cancer lineages are VRK1, UBR7, and MTA1. Each is linked with IFI27L1 in more than 6 cancer types. Because this analysis shows association rather than direction, both IFI27L1-to-partner and partner-to-IFI27L1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IFI27L1 versus VRK1 in LSCC, with a Pearson correlation of 0.59.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IFI27L1→partner) and Y-score (partner→IFI27L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	VRK1 →	+0.532	+0.385	<.001	<.001	3	7
GBM	UBR7 →	+0.377	+0.382	<.001	<.001	3	6
HNSC	MTA1 →	+0.386	+1.126	<.001	<.001	3	6
LSCC	PPP4R3A →	+0.329	+0.474	<.001	<.001	3	6
COAD	MTHFD1 →	+0.290	+0.694	<.001	<.001	3	6
GBM	BAG5 →	+0.362	+0.410	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,416 associations by consensus.

IFI27L1 vs VRK1 — LSCC

Explore this scatter interactively →