IFFO1

Across TCGA patient cohorts, IFFO1 protein abundance is significantly associated with the RNA expression of many other genes, with 2,519 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IFFO1-associated genes across cancer lineages are RAD50, UBE2D2, and RMND1. Each is linked with IFFO1 in more than 1 cancer types. Because this analysis shows association rather than direction, both IFFO1-to-partner and partner-to-IFFO1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IFFO1 versus RAD50 in HNSC, with a Pearson correlation of -0.73.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IFFO1→partner) and Y-score (partner→IFFO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RAD50 →	-0.572	-0.843	.001	.001	3	2
CCRCC	UBE2D2 →	-0.563	-0.340	<.001	.005	3	2
CCRCC	RMND1 →	-0.872	-0.553	<.001	.001	3	2
CCRCC	ENTPD3 →	-0.563	-0.457	.001	.003	3	2
CCRCC	FBXW11 →	-0.293	-0.366	<.001	.002	3	2
GBM	CD200 →	-0.748	-0.281	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,519 associations by consensus.

IFFO1 vs RAD50 — HNSC

Explore this scatter interactively →