IER3-AS1

Across TCGA patient cohorts, IER3-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,394 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible IER3-AS1-associated proteins across cancer lineages are SHC1_Y427, SNIP1_S76, and STX17_S289. Each is linked with IER3-AS1 in more than 5 cancer types. Because this analysis shows association rather than direction, both IER3-AS1-to-partner and partner-to-IER3-AS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IER3-AS1 versus SHC1_Y427 in LSCC, with a Pearson correlation of 0.27.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IER3-AS1→partner) and Y-score (partner→IER3-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SHC1_Y427 →	+0.731	+0.360	.002	.001	3	6
LSCC	SNIP1_S76 →	-0.742	-0.333	<.001	<.001	3	6
CCRCC	STX17_S289 →	-0.815	-1.000	<.001	<.001	3	6
LSCC	CIR1_S394 →	-0.914	-0.481	<.001	<.001	3	6
LUAD	AFF4_S694 →	+0.630	+0.482	.003	<.001	3	6
CCRCC	DBNL_S283 →	+0.949	+0.743	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,394 associations by consensus.

IER3-AS1 vs SHC1_Y427 — LSCC

Explore this scatter interactively →