IER2

Across TCGA patient cohorts, IER2 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,179 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible IER2-associated proteins across cancer lineages are YJU2_S179, ZC3H13_S473, and ZCCHC8_S658. Each is linked with IER2 in more than 6 cancer types. Because this analysis shows association rather than direction, both IER2-to-partner and partner-to-IER2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IER2 versus YJU2_S179 in HNSC, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IER2→partner) and Y-score (partner→IER2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	YJU2_S179 →	+0.772	+0.609	<.001	<.001	3	7
GBM	ZC3H13_S473 →	+0.492	+0.630	<.001	<.001	3	6
GBM	ZCCHC8_S658 →	+0.499	+0.747	<.001	<.001	3	6
CCRCC	ZNF638_S383 →	+1.162	+1.178	<.001	<.001	3	6
LSCC	SON_S94 →	+0.558	+0.471	.003	.004	3	6
PDAC	NCOA6_S1481 →	+0.878	+0.551	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,179 associations by consensus.

IER2 vs YJU2_S179 — HNSC

Explore this scatter interactively →