IDS

Across TCGA patient cohorts, IDS RNA expression is significantly associated with the protein abundance of many other proteins, with 12,194 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible IDS-associated proteins across cancer lineages are RPL6, GDI1, and PLS3. Each is linked with IDS in more than 6 cancer types. Because this analysis shows association rather than direction, both IDS-to-partner and partner-to-IDS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IDS versus RPL6 in LUAD, with a Pearson correlation of -0.29.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IDS→partner) and Y-score (partner→IDS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RPL6 →	-0.408	-0.692	.001	<.001	3	7
BRCA	GDI1 →	+0.337	+0.467	<.001	.001	3	6
LUAD	PLS3 →	+0.576	+0.678	<.001	<.001	3	6
OV	PRPF4B →	-0.321	-0.741	<.001	<.001	3	5
LSCC	RBM25 →	-0.240	-0.397	<.001	.001	3	5
LUAD	EMD →	+0.323	+0.474	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,194 associations by consensus.

IDS vs RPL6 — LUAD

Explore this scatter interactively →